Sunday, October 28, 2007

White Flour Contains Diabetes-Causing Alloxin


You may want to think twice before e
ating your next sandwich on white
bread. Studies show that alloxan, the
chemical that makes white flour look
"clean" and "beautiful," destroys the
beta cells of the pancreas. That's right;
you may be devastating your pancreas
and putting yourself at risk for diabetes,
all for the sake of eating "beautiful"
flour. Is it worth it? Scientists have
known of the alloxan-diabetes
connection for years; in fact,
researchers who are studying diabetes
commonly use the chemical to induce
the disorder in lab animals. In the
research sense, giving alloxan to an
animal is similar to injecting that
animal with a deadly virus, as both
alloxan and the virus are being used
specifically to cause illness. Every day,
consumers ingest foods made with
alloxan-contaminated flour. Would
they just as willingly consume foods
tainted with a deadly virus? Unless
they had a death wish, they probably
would not. Unfortunately, most
consumers are unaware of alloxan
and its potentially fatal link to diabetes
because these facts are not well
publicized by the food industry.

How does alloxan cause diabetes?
According to Dr. Hari Sharma's
Freedom from Disease, the uric acid
derivative initiates free radical damage
to DNA in the beta cells of the
pancreas, causing the cells to
malfunction and die. When these
beta cells fail to operate normally,
they no longer produce enough
insulin, or in other words, they
cause one variety of adult-onset
type 2 diabetes. Alloxan's harmful
effects on the pancreas are so severe
that the Textbook of Natural Medicine
calls the chemical "a potent beta-cell
toxin." However, even though the
toxic effect of alloxan is common
scientific knowledge in the research
community, the FDA still allows
companies to use it when processing
foods we ingest.

The FDA and the white flour industry
could counter-argue that, if alloxan
were to cause diabetes, a higher
proportion of Americans would be
diabetic. After all, more consumers
consume white flour on a regular
basis than are actually diabetic. This
point is valid, but it does not disprove
the alloxan-diabetes connection.
While alloxan is one cause of adult-onset
type 2 diabetes, it is of course not
the only cause. As the Textbook of
Natural Medicine states, "current
theory suggests an hereditary beta-cell
predisposition to injury coupled with
some defect in tissue regeneration
capacity" may be a key cause. For
alloxan to cause injury to an individual's
beta cells, the individual must have
the genetic susceptibility to injury.
This is similar to the connection between
high-cholesterol foods and heart disease.
Eating high-cholesterol foods causes
heart disease, especially in people who
have family histories of heart disease.
The link between alloxan and diabetes
is as clear and solid as the link between
cholesterol and heart disease.

If you've been eating white bread for
years and you have a family history of
diabetes, all hope is not lost for you.
Studies show that you can reverse the
effects of alloxan by supplementing
your diet with vitamin E. According to
Dr. Gary Null's Clinicians Handbook
of Natural Healing, vitamin E effectively
protected lab rats from the harmful
effects of administered alloxan. Now,
you're not a lab rat, but you're a
mammal and vitamin E is definitely
worth adding to your daily regimen
of nutritional supplements, especially
if you have a history of eating foods
made with white flour and are at high
risk for diabetes.

Even if you are already diabetic,
some simple changes to your diet can
help treat your diabetes. First of all,
stop eating foods made with white
flour. Even though you already have
diabetes, vitamin E supplements can
still help you, as can many common
foods. Garlic, for example, does wonders
for diabetes. As Dr. Benjamin Lau states
in his book Garlic for Health, "When
fed garlic, the rabbits' elevated blood
sugar dropped almost as much as it
did when they were given the antidiabetic
drug tolbutamide. Researchers postulated
that garlic may improve the insulin effect."

If you can't handle the taste of natural
garlic, you can take it in widely available
supplements. Aloe vera is a traditional
diabetic remedy in the Arabian Peninsula,
and its therapeutic characteristics are
now gaining worldwide acceptance in
the treatment of diabetes. According to
both human and animal research studies,
aloe vera lowers blood glucose levels by
an unknown mechanism. According to
the Clinicians Handbook of Natural
Healing, this natural hypoglycemic effect
extended over a period of 24 hours. Adding
onions to your diet (along with the garlic)
can also significantly reduce your blood
sugar level. Additionally, as Dr. Michael
T. Murray writes in The Healing Power of
Herbs, studies show that ginseng controls
glucose in both diabetic humans and
diabetic laboratory animals.

It all comes down to asking if putting
yourself at risk for diabetic coma,
blindness, limb amputation and death
is worth eating white bread. If you're
willing to risk your quality of life and
your life itself, then go ahead and eat
all the foods made with white flour you
want. However, if you want to stop poisoning
yourself with alloxan, a known toxic
chemical, then make a few simple dietary
changes. Eat groceries made with whole
-grain wheat flour, not processed white flour

Animal experiments have shown that
animals which have their Beta cells
destroyed by alloxan are able to regenerate
Beta cells after a few months when taking
GS, a herb grown in India. The Beta cell
is the cell that produces insulin. Diabetics
needing insulin treatment (Type 1) have
been able to decrease their insulin after GS
therapy. A Physicians Guide to Natural
Health Products That Work By James
Howenstine MD, page 112

In the mid-1980s, however (when herbal
remedies again were popular), pata de
vaca's continued use as a natural insulin
substitute was reiterated in two Brazilian
studies. Both studies reported in vivo
hypoglycemic actions in various animal
and human models. Chilean research in
1999 reported the actions of pata de vaca
in diabetic rats. Their study determined
that pata de vaca was found to "elicit
remarkable hypoglycemic effects," and
brought about a "decrease of glycemia in
alloxan diabetic rats by 39%." In 2002,
two in vivo studies on the blood sugar-lowering e
ffects of pata de vaca were conducted by two
separate research groups in Brazil. The first
study reported "a significant blood glucose-
lowering effect in normal and diabetic rats."...
The Healing Power of Rainforest Herbs by
Leslie Taylor, page 382

When beta cells in the pancreas fail to
secrete enough insulin, the body loses
its ability to metabolize carbohydrates
and to reduce glucose levels in the
bloodstream. Researchers believe that
some people have weak free radical defenses
in these beta cells, and that free radical
damage to DNA in beta cells, resulting in
dysfunction or cell death, helps cause
maturity-onset diabetes. It is known, for
example, that many chemicals including
alloxan, paraquat, and certain chemotherapeutic
agents can stimulate excessive production of
oxy radicals in the nuclei of beta cells.
Freedom From Disease by Hari Sharma MD,
page 94

...nearly two decades later, researchers
at RNT Medical College in India induced
diabetes in rabbits with intravenous injections
of alloxan. When fed garlic, the rabbits'
elevated blood sugar dropped almost as much
as it did when they were given the antidiabetic
drug tolbutamide. Researchers postulated
that garlic may improve the insulin effect
by either increasing the pancreatic secretion
of insulin or by releasing bound insulin.
Garlic for Health by Benjamin Lau MD PhD,
page 22

Commercial yeasted breads, even the
whole-grain varieties, often have other
problems. They typically contain flour
bleach, which forms alloxan, a compound
known to cause diabetes in animals by
destroying the beta cells of the pancreas
(Clinical Nutrition Newsletter, Dec. 1982). ...
Healing With Whole Foods by Paul Pitchford,
page 452

Insulin dependent diabetes mellitus is
generally recognized to be due to an insulin
deficiency.1 Although the exact cause is
unknown, current theory suggests an
hereditary beta-cell predisposition to injury
coupled with some defect in tissue regeneration
capacity. Causes of injury are most likely
hydroxyl and other free radicals, viral infection,
and autoimmune reactions. alloxan, the uric
acid derivative used to induce experimental
diabetes in animals, is a potent beta-cell toxin,
causing destruction via hydroxyl radical
formation. Textbook of Natural Medicine
Volumes 1-2 by Joseph E Pizzorno and Michael T
Murray, page 1197

In this study, mice received intraperitoneally
melatonin in doses ranging from 100 to 450
mg/kg. Results showed that such treatment
proved plasma glucose increase due to alloxan-
induced pancreatic toxicity. The Clinicians
Handbook of Natural Healing by Gary Null PhD,
page 88

Bleached white flour. Not only have the bran
and germ been stripped away, but bleached
flour also contains a substance from the
flour bleach (alloxan) which causes diabetes
in animals. Unbleached white flour should
also be avoided since it is stripped of essential
nutrients. The Enzyme Cure by Lita Lee with
Lisa Turner & Burton Goldberg, page 123

Aloe vera also exhibits a hypoglycemic effect
in both normal and alloxan-induced diabetic
mice. A small human study shows benefit in
diabetics. Five patients with non-insulin
dependent diabetes ingested half a teaspoonful
of aloe 4 times daily for 14 weeks. Fasting blood
sugar in every patient fell from a mean of 273 to
151 mg/dl with no change in body weight. The
authors concluded that aloe lowers blood glucose
levels by an unknown mechanism.... Textbook of
Natural Medicine, volumes 1-2 by Joseph E
Pizzorno and Michael T Murray, page 587

Results of this study showed that rats given
vitamin E before being administered either
streptozotocin or alloxan provided protection
against the diabetogenic effects of each. It was
also observed that rats with a depleted antioxidant
state due to a vitamin E and selenium-deficient
diet showed increased diabetogenic susceptibility
to normally nondiabetogenic doses of streptozotocin.
The Clinicians Handbook of Natural Healing by
Gary Null PhD, page 312

Noting that the dried sap of the aloe plant to
be a traditional diabetic remedy in the Arabian
peninusla, this study examined its ability to
reduce blood glucose levels in 5 non-insulin-
dependent diabetics and in Swiss albino mice
made diabetic with alloxan. Results showed
that the intake of 1/2 teaspoon of aloes daily
for 4-14 weeks significantly reduced the fasting
serum glucose level fell in all patients. Fasting
plasma glucose was significantly reduced in
diabetic mice by glibenclamide and aloes after
3 days. The Clinicians Handbook if Natural
Healing by Gary Null PhD, page 369

This study examined the effects of exudate
of Aloe barbadensis leaves (oral administration
of 500 mg/kg) and its bitter principle
(ip administration of 5 mg/kg) on plasma
glucose levels of alloxan-diabetic mice.
Results showed that the hypoglycemic
effect of a single oral dose of aloes on serum
glucose level was insignificant in while that
of the bitter principle was highly significant
and extended over a period of 24 hours. The
Clinicians Handbook of Natural Healing by
Gary Null PhD, page 369

Ginseng exerts numerous pharmacological
effects in humans and laboratory animals,
including ... improved glucose control in
humans and diabetic (alloxan-induced)
rats; The Healing Power of Herbs by
Michael T Murray ND, page 269

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